| Seng | Chinese name meaning 'good' or 'virtuous' |
| Senor | A Spanish title of respect meaning mister. |
| Serek | Repeated of Births, Lordly |
| Serg | Short form of Sergei, meaning 'victorious' |
| Serghei | Russian name meaning 'victorious' or 'triumphant' |
| Serj | Short form of Sergei, meaning 'victorious' |
| Sev | A short form of Seven, meaning the number seven. |
| Seyi | Yoruba name meaning 'gift of God' |
| Seymore | From Saint Maur |
| Shale | A Mountain Rock |
| Shamier | Flint-like, The Shamir Stone |
| Shanette | Loving will to Give All |
| Sharir | A name of Hebrew origin meaning the body. |
| Shark | Nickname for Sharon, meaning 'bitter' or 'fierce' |
| Shaven | Having a smooth, hairless surface, often referring to the head or face. |
| Shawnte | Place of Stones |
| Shayden | Variant of Hayden, meaning 'brilliant' or 'fiery'. |
| Shedrick | Aku's Command; Variation of .... |
| Shell | A name referring to a hard protective casing. |
| Shemar | A name meaning guardian or protected one. |
| Shenandoah | A name meaning daughter of the stars. |
| Shequille | The Royal Princes |
| Sheraan | Variant of Sheran, meaning 'peaceful' or 'tranquil'. |
| Sherod | Wild Man, Clearer of the Land |
| Sherrick | One who has Already Left |
| Sherril | Shire on a Hill |
| Sherrill | A name meaning bright or beloved meadow. |
| Shevaughn | An Irish name meaning God is gracious. |
| Shevon | A variant name meaning God is gracious. |
| Shia | A follower of the Islamic faith. |
| Shikoba | A name meaning feather or wing. |
| Shoe | A covering worn on the human foot. |
| Shone | Yahweh is Merciful or Gracious |
| Shonti | Variant of Shonti, meaning 'peaceful' or 'calm'. |
| Shooter | One who Shoots with a Gun or Camera |
| Shorn | Having hair cut or removed, often referring to the head or face. |
| Shunda | A name meaning smooth or sleek. |
| Shyheim | Variant of Shyheim, meaning 'peaceful' or 'tranquil'. |
| Sicily | From the Island |
| Sidi | Variant of Sidi, meaning 'master' or 'lord'. |